Also known as Gamma-glutamyl transpeptidase
Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT, gamma-glutamyl transpeptidase; ) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione as well as drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a pro-oxidant role, with regulatory effects at various levels in ce
γ-谷氨酰转肽酶(Gamma-glutamyltransferase)又称γ-谷氨酰转移酶、GGT、γ-GT、EC 2.3.2.2,是一种轉移酶,在γ-谷氨酸官能团从谷胱甘肽等分子上转移至受体時起催化作用,受体可能是一种氨基酸、一种肽或水。γ-谷氨酰转肽酶在γ-谷氨酰循环(Gamma-glutamyl cycle)中起着关键作用。许多人體组织中都有γ-谷氨酰转肽酶,例如肝脏。
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).