melperone
Also known as FG-5111
Melperone (Bunil (PT), Buronil (AT, BE, CZ, DK, FI†, NL†, NO†, SE), Eunerpan (DE)) is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. It first entered clinical use in 1960s.
Key facts
- Drug.verifiedrevid
- 447616990
- Drug.IUPAC_name
- 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one
- Drug.image
- Melperone.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula of melperone
- Drug.width
- 250
- Drug.image2
- Melperone 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Space-filling model of the melperone molecule
- Drug.width2
- 250
- Drug.tradename
- Buronil
- Drug.legal_status
- Rx-only
~4 min read
Article
8 sectionsContents
- Marketing and indications
- Adverse effects
- Interactions
- Pharmacology
- Synthesis
- See also
- References
- External links
Melperone (Bunil (PT), Buronil (AT, BE, CZ, DK, FI†, NL†, NO†, SE), Eunerpan (DE)) is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. It first entered clinical use in 1960s.
==Marketing and indications== It has been tried in treatment-resistant cases of schizophrenia with some (albeit limited) success. It has also been reported effective in the treatment of L-DOPA and other forms of psychosis in Parkinson's disease (although a multicentre, double-blind, placebo-controlled study conducted in 2012 failed to support these findings). It is also known to possess anxiolytic properties. It is marketed in the following countries: Austria Czech Republic Denmark Estonia Finland Germany Iceland Lithuania Latvia Portugal Sweden