Givinostat, sold under the brand name Duvyzat is a medication used for the treatment of Duchenne muscular dystrophy. It is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a histone deacetylase (HDAC) inhibitor that works by targeting pathogenic processes to reduce inflammation and loss of muscle.
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451563965 | image = Givinostat structure.svg | image_class = skin-invert-image | alt = | width = | caption =
| pronounce = | tradename = Duvyzat | Drugs.com = | MedlinePlus = a624025 | DailyMedID = Givinostat | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = Histone deacetylase inhibitor | ATC_prefix = M09 | ATC_suffix = AX14 | ATC_supplemental =
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).