Article
8 sectionsContents
- Mechanism of action
- PPARγ transactivation
- PPARγ transrepression
- Members of the class
- Uses
- Research
- Side effects and contraindications
- References
thumb|Functional group
The thiazolidinediones , abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered C3NS ring. The term usually refers to a family of drugs used in the treatment of diabetes mellitus type 2 that were introduced in the late 1990s. As of 2024, there are two FDA-approved drugs in this class, pioglitazone and rosiglitazone.