glitazone
Sign in to saveAlso known as thiazolidinediones, glitazones, thiazolidinedione
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Research
15,902 papers- Does glitazone treatment have a role on the prevention of Parkinson's disease in adult diabetic population? A systematic review.Metabolic brain disease · 2020
- Thiazolidinediones.The New England journal of medicine · 2004
- Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson's Disease.International journal of molecular sciences · 2021
- Glitazone loaded fat enhances adiponectin production and inhibits breast cancer cell proliferation.Molecular biology reports · 2019
- The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.Molecules (Basel, Switzerland) · 2021
via PubMed
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Encyclopedic overview
8 sectionsContents
- Mechanism of action
- PPARγ transactivation
- PPARγ transrepression
- Members of the class
- Uses
- Research
- Side effects and contraindications
- References
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The thiazolidinediones , abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered C3NS ring. The term usually refers to a family of drugs used in the treatment of diabetes mellitus type 2 that were introduced in the late 1990s. As of 2024, there are two FDA-approved drugs in this class, pioglitazone and rosiglitazone.
Excerpted from Wikipedia’s “glitazone” article, available under the CC BY-SA 4.0 licence.