GRB7
Sign in to saveAlso known as entrez:2886, growth factor receptor bound protein 7
Growth factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene.
Gene data
GRB7- Name
- growth factor receptor bound protein 7
- Type
- protein-coding
- Position
- 39,737,490–39,747,292 (+)
- Ensembl
- ENSG00000141738
- RefSeq RNA
- NM_001030002.3, NM_001242442.2, NM_001242443.2, NM_001330207.2, NM_005310.5
- RefSeq protein
- NP_001025173.1, NP_001229371.2, NP_001229372.1, NP_001317136.1, NP_005301.2
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
growth factor receptor bound protein 7
- Symbol
- GRB7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:39,737,490-39,747,292
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~2 min read
Encyclopedic overview
6 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- Further reading
- External links
Growth factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene.
== Function ==
Excerpted from Wikipedia’s “GRB7” article, available under the CC BY-SA 4.0 licence.