File:Somatotropine.GIF · Wikimedia Commons · See Wikimedia Commons
growth hormone
Sign in to saveAlso known as IPR034975, GH, somatropin, growth hormones
peptide hormones that stimulate growth, cell reproduction, and cell regeneration
Growth hormone is a chemical messenger in your body that tells your cells to grow, multiply, and repair themselves. It matters because without it, your body wouldn't be able to develop properly or maintain healthy tissues throughout your life.
AI-generated from the Wikipedia summary — may contain errors.
Research
156,470 papers- Growth-hormone-releasing hormone.ReviewClinical chemistry · 1990Vance ML
- Growth hormone: revisited.ReviewFertility and sterility · 1992Christman GM, Halme JKDOI: 10.1016/s0015-0282(16)54768-2
- Growth hormone and prolactin: So much still to learn.Journal of neuroendocrinology · 2020Le Tissier PR, Grattan DRDOI: 10.1111/jne.12909
- Growth hormone suppression in endothelial dysfunction.ReviewCell cycle (Georgetown, Tex.) · 2025Barabutis NDOI: 10.1080/15384101.2025.2531893
- GROWTH HORMONE.ReviewAnnual review of pharmacology · 1965MATSUZAKI F, RABEN MSDOI: 10.1146/annurev.pa.05.040165.001033
- Growth hormone deficiency.ReviewAnnals of clinical biochemistry · 1987Gunn IDOI: 10.1177/000456328702400501
- Growth hormone and puberty.ReviewThe Journal of endocrinology · 1992Ogilvy-Stuart AL, Shalet SMDOI: 10.1677/joe.0.1350405
- Growth hormone, 1988.ReviewThe Journal of clinical investigation · 1988Thorner MO, Vance MLDOI: 10.1172/JCI113673
via PubMed
Wikidata facts
- Instance of
- protein family
- Subclass of
- hormone
- Image
- Somatotropine.GIF
Show 5 more facts
- found in taxon
- Vertebrata
- topic's main category
- Category:Growth hormones
- Commons category
- Growth hormones
- MCN code
- 3003.39.11
Sources (7)
via Wikidata · CC0
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Encyclopedic overview
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of insulin-like growth factor 1 (IGF-1) and increases the concentration of glucose and free fatty acid. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.
A recombinant form of HGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. In the United States, it is only available legally from pharmacies by prescription from a licensed health care provider. In recent years in the United States, some health care providers are prescribing growth hormone in the elderly to increase vitality. While legal, the efficacy and safety of this use for HGH has not been tested in a clinical trial. Many of the functions of HGH remain unknown.
Excerpted from Wikipedia’s “growth hormone” article, available under the CC BY-SA 4.0 licence.