SSTR2
Sign in to saveAlso known as Somatostatin receptor 2
protein-coding gene in the species Homo sapiens
Gene data
SSTR2- Name
- somatostatin receptor 2
- Type
- protein-coding
- Position
- 73,164,253–73,176,633 (+)
- Aliases
- SST2
- Ensembl
- ENSG00000180616
- RefSeq RNA
- NM_001050.3
- RefSeq protein
- NP_001041.1
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
G protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerneuropeptide signaling pathwaynegative regulation of cell population proliferationnegative regulation of cell population proliferationsomatostatin signaling pathwaycellular response to glucocorticoid stimulus
Molecular function
Pathways
cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Growth hormone synthesis, secretion and action - Homo sapiens (human)Gastric acid secretion - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsGPCR downstream signallingG alpha (i) signalling events
via MyGene.info
Gene · Ensembl
somatostatin receptor 2
- Symbol
- SSTR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:73,164,253-73,176,633
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 37427
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6752
- genomic end
- 71167185
- genomic start
- 73165010
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.1
- expressed in
- prefrontal cortex
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