GHSR

Name

growth hormone secretagogue receptor

Type

protein-coding

Position

172,442,551–172,448,456 (−)

Aliases

GHDP, GHS-R1a, GHSR-1a

Ensembl

ENSG00000121853

RefSeq RNA

NM_004122.2, NM_198407.2

RefSeq protein

NP_004113.1, NP_940799.1

This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010].

via MyGene.info

Gene · Ensembl

growth hormone secretagogue receptor

Symbol

GHSR

Biotype

Protein coding

Organism

Homo sapiens

Location

3:172,442,551-172,448,456

Strand

Reverse (−)

Assembly

GRCh38