HES6
Sign in to saveAlso known as C-HAIRY1, HES-6, bHLHb41, bHLHc23, hes family bHLH transcription factor 6
Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene.
Gene data
HES6- Name
- hes family bHLH transcription factor 6
- Type
- protein-coding
- Position
- 238,237,903–238,240,680 (−)
- Aliases
- C-HAIRY1, HES-6, bHLHb41, bHLHc23
- Ensembl
- ENSG00000144485
- RefSeq RNA
- NM_001142853.3, NM_001282434.2, NM_018645.6
- RefSeq protein
- NP_001136325.1, NP_001269363.1, NP_061115.2
This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Dec 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
hes family bHLH transcription factor 6
- Symbol
- HES6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:238,237,903-238,240,680
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 23111
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55502
- genomic end
- 239149303
- genomic start
- 239146908
- chromosome
- human chromosome 2
- cytogenetic location
- 2q37.3
- expressed in
- anterior cingulate cortex
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene.
== Interactions ==
Excerpted from Wikipedia’s “HES6” article, available under the CC BY-SA 4.0 licence.