HESX1
Sign in to saveAlso known as ANF, CPHD5, RPX, HESX homeobox 1
Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene.
Gene data
HESX1- Name
- HESX homeobox 1
- Type
- protein-coding
- Aliases
- ANF, CPHD5, RPX
This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1-related growth hormone deficiency, and combined pituitary hormone deficiency. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20831
- exact match
- identifiers.org/ncbigene/8820
- genomic end
- 57227606
- genomic start
- 57197838
- cytogenetic location
- 3p14.3
via Wikidata · CC0
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Article
4 sectionsContents
- Clinical significance
- References
- Further reading
- External links
Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene.
Expression of HEX1 and HESX1 marks the anterior visceral endoderm of the embryo. The AVE is an extra-embryonic tissue, key to the establishment of the anterior-posterior body axis.