HEYL
Sign in to saveAlso known as HESR3, HEY3, HRT3, bHLHb33, hes related family bHLH transcription factor with YRPW motif-like, hes related family bHLH transcription factor with YRPW motif like
Hairy/enhancer-of-split related with YRPW motif-like protein is a protein that in humans is encoded by the HEYL gene.
Gene data
HEYL- Name
- hes related family bHLH transcription factor with YRPW motif like
- Type
- protein-coding
- Aliases
- HESR3, HEY3, HRT3, bHLHb33
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
hes related family bHLH transcription factor with YRPW motif like
- Symbol
- HEYL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:39,608,861-39,639,686
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8494
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26508
- cytogenetic location
- 1p34.2
- genomic end
- 39639643
- chromosome
- human chromosome 1
- genomic start
- 39623435
- expressed in
- left ventricle
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Hairy/enhancer-of-split related with YRPW motif-like protein is a protein that in humans is encoded by the HEYL gene.
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Excerpted from Wikipedia’s “HEYL” article, available under the CC BY-SA 4.0 licence.