HMGA1
Sign in to saveAlso known as HMG-R, HMGA1A, HMGIY, high mobility group AT-hook 1
High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.
Gene data
HMGA1- Name
- high mobility group AT-hook 1
- Type
- protein-coding
- Position
- 34,235,618–34,246,236 (+)
- Aliases
- HMG-R, HMGA1A, HMGIY
- Ensembl
- ENSG00000137309
- RefSeq RNA
- NM_001319077.2, NM_001319078.2, NM_001319079.2, NM_001319080.2, NM_001319081.2
- RefSeq protein
- NP_001306006.1, NP_001306007.1, NP_001306008.1, NP_001306009.1, NP_001306010.1
This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
high mobility group AT-hook 1
- Symbol
- HMGA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:34,235,618-34,246,236
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- HMGA1.png
Show 8 more facts
- HomoloGene ID
- 128226
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3159
- cytogenetic location
- 6p21.31
- genomic end
- 34214008
- genomic start
- 34204650
- chromosome
- human chromosome 6
- expressed in
- appendix
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.
== Function ==
Excerpted from Wikipedia’s “HMGA1” article, available under the CC BY-SA 4.0 licence.