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GeneQ18027130· pop 6· linked from 813 articles

Also known as HOX1, HOX1.3, HOX1C, homeobox A5

Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.

Gene data

HOXA5
Name
homeobox A5
Type
protein-coding
Position
27,141,052–27,143,681 (−)
Aliases
HOX1, HOX1.3, HOX1C
RefSeq RNA
NM_019102.4
RefSeq protein
NP_061975.2

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

homeobox A5

Symbol
HOXA5
Biotype
Protein coding
Organism
Homo sapiens
Location
7:27,141,052-27,143,719
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein HOXA5 PDB 1hom.png
Show 6 more facts
HomoloGene ID
40726
genomic end
27143681
genomic start
27180671
cytogenetic location
7p15.2
Commons category
HOXA5
Sources (4)

via Wikidata · CC0

~2 min read

Article

5 sections
Contents
  • Function
  • Clinical significance
  • See also
  • References
  • External links

Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.

== Function ==

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via Wikidata sitelinks · CC0

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