HOXB3
Sign in to saveAlso known as HOX2, HOX2G, Hox-2.7, homeobox B3
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
In the Vinony graph
Within Vinony's link graph, HOXB3 is referenced by 813 other articles, and connects out to PubMed, human chromosome 17 and homeobox.
It is catalogued under topics including Genes on human chromosome 17 and Transcription factors.
Its subject is documented across 5 Wikipedia language editions.
Gene data
HOXB3- Name
- homeobox B3
- Type
- protein-coding
- Position
- 48,548,870–48,604,912 (−)
- Aliases
- HOX2, HOX2G, Hox-2.7
- Ensembl
- ENSG00000120093
- RefSeq RNA
- NM_001330322.2, NM_001330323.1, NM_001384747.1, NM_001384749.1, NM_001384750.1
- RefSeq protein
- NP_001317251.1, NP_001317252.1, NP_001371676.1, NP_001371678.1, NP_001371679.1
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
homeobox B3
- Symbol
- HOXB3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,548,870-48,604,912
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1617
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3213
- chromosome
- human chromosome 17
- genomic start
- 46626232
- genomic end
- 46682274
- cytogenetic location
- 17q21.32
- expressed in
- endometrium
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).
Excerpted from Wikipedia’s “HOXB3” article, available under the CC BY-SA 4.0 licence.