HOXB3
Sign in to saveAlso known as HOX2, HOX2G, Hox-2.7, homeobox B3
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Gene data
HOXB3- Name
- homeobox B3
- Type
- protein-coding
- Position
- 48,548,870–48,604,912 (−)
- Aliases
- HOX2, HOX2G, Hox-2.7
- Ensembl
- ENSG00000120093
- RefSeq RNA
- NM_001330322.2, NM_001330323.1, NM_001384747.1, NM_001384749.1, NM_001384750.1
- RefSeq protein
- NP_001317251.1, NP_001317252.1, NP_001371676.1, NP_001371678.1, NP_001371679.1
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
homeobox B3
- Symbol
- HOXB3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,548,870-48,604,912
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).
Excerpted from Wikipedia’s “HOXB3” article, available under the CC BY-SA 4.0 licence.