HOXB3
Sign in to saveAlso known as HOX2, HOX2G, Hox-2.7, homeobox B3
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Gene data
HOXB3- Name
- homeobox B3
- Type
- protein-coding
- Aliases
- HOX2, HOX2G, Hox-2.7
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
homeobox B3
- Symbol
- HOXB3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,548,870-48,604,912
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1617
- exact match
- identifiers.org/ncbigene/3213
- genomic start
- 46626232
- genomic end
- 46682274
- cytogenetic location
- 17q21.32
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- See also
- References
- Further reading
- External links
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).