HOXB7

Also known as HHO.C1, HOX2, HOX2C, Hox-2.3, homeobox B7

Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

Gene data

HOXB7

Name: homeobox B7
Type: protein-coding
Position: 48,607,222–48,633,572 (−)
Aliases: HHO.C1, HOX2, HOX2C, Hox-2.3
Ensembl: ENSG00000260027
RefSeq RNA: NM_004502.4
RefSeq protein: NP_004493.3

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II anterior/posterior pattern specification positive regulation of transcription by RNA polymerase II embryonic organ development positive regulation of branching involved in ureteric bud morphogenesis

Molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity

Cellular component

chromatin nucleus nucleus nucleus nucleoplasm nuclear body

via MyGene.info

Gene · Ensembl

homeobox B7

Symbol: HOXB7
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:48,607,222-48,633,572
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein HOXB7 PDB 1ahd.png

Show 5 more facts

HomoloGene ID: 55828
exact match: identifiers.org/ncbigene/3217
genomic end: 46710934
genomic start: 48607232
cytogenetic location: 17q21.32

Sources (4)

via Wikidata · CC0

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Article

6 sections

Contents

Function
Interactions
See also
References
Further reading
External links

Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

== Function == This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.