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hydrocodone/paracetamol
Sign in to saveAlso known as Vicodin
Hydrocodone/paracetamol (also known as hydrocodone/acetaminophen) is the combination of the pain medications hydrocodone (an opioid) and paracetamol (acetaminophen). It is used to treat moderate to severe pain. It is taken by mouth. Recreational use is common in the United States.
Chemical data
- Formula
- C26H30N2O5
- Molecular weight
- 450.5 g/mol
- IUPAC name
- (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;N-(4-hydroxyphenyl)acetamide
- SMILES
- CC(=O)NC1=CC=C(C=C1)O.CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
- InChIKey
- DQGPYIDMOHQZSY-RNWHKREASA-N
- Polar surface area
- 88.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
~8 min read
Encyclopedic overview
19 sectionsContents
- Uses
- Medical
- Recreational
- Pregnancy and breastfeeding
- Kidney and liver impairment
- Side effects
- Most common
- Less common
- Boxed warning
- Overdose
- Interactions
- Pharmacology
- Hydrocodone
- Paracetamol
- Society and culture
- Legal status
- Popular culture
- Brand names
- References
Hydrocodone/paracetamol (also known as hydrocodone/acetaminophen) is the combination of the pain medications hydrocodone (an opioid) and paracetamol (acetaminophen). It is used to treat moderate to severe pain. It is taken by mouth. Recreational use is common in the United States.
Common side effects include dizziness, sleepiness, constipation, and vomiting. Serious side effects include addiction, decreased rate of breathing, low blood pressure, severe allergic reactions, and liver failure. Use during pregnancy may harm the fetus. Use with alcohol is not recommended. Hydrocodone works by binding to the mu-opioid receptor. How paracetamol works is unclear but may involve blocking the creation of prostaglandins.
Excerpted from Wikipedia’s “hydrocodone/paracetamol” article, available under the CC BY-SA 4.0 licence.