hydrolase
Sign in to saveAlso known as EC 3, hydrolytic enzyme, hydrolases
In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond:
Research
1,654,217 papers- The SGNH hydrolase family: a template for carbohydrate diversity.Glycobiology · 2022
- Emerging Strategies in Polyethylene Terephthalate Hydrolase Research for Biorecycling.ChemSusChem · 2021
- Alpha/beta hydrolase fold: an update.Protein and peptide letters · 2009
- Alpha/Beta-hydrolase fold enzymes: structures, functions and mechanisms.Current protein & peptide science · 2000
- Peptide-Based Catalyst Mimicking Hydrolase Enzyme.Journal of peptide science : an official publication of the European Peptide Society · 2025
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Encyclopedic overview
7 sectionsContents
- Nomenclature
- Classification
- Clinical considerations
- Membrane-associated hydrolases
- Etymology and pronunciation
- See also
- References
In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: \ce{A-B + H2O} \quad \xrightarrow[\text{ hydrolase }]{} \quad \ce{A-OH + B-H}
This typically results in dividing a larger molecule into smaller molecules. Some common examples of hydrolase enzymes are esterases including lipases, phosphatases, glycosidases, peptidases, and nucleosidases.
Excerpted from Wikipedia’s “hydrolase” article, available under the CC BY-SA 4.0 licence.