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hyperinsulinism

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Hyperinsulinism refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and blood levels are closely related to the level of glucose in the blood, so that a given level of insulin can be normal for one blood glucose level but low or high for another. Hyperinsulinism can be associated with several types of medical problems, which can be roughly divided into two broad and largely non-overlapping categories: those tending toward reduced sensitivity to insulin and high blood glucose levels (hyperglycemia), and those tending toward excessive insulin s

Key facts

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Insulin
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Endocrinology

via Wikipedia infobox

Research

120,302 papers

via PubMed

Wikidata facts

Instance of
phenotype
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health specialty
endocrinology
risk factor
smoking
Sources (3)

via Wikidata · CC0

~4 min read

Encyclopedic overview

7 sections
Contents
  • Signs and symptoms
  • Diagnosis
  • Diminished sensitivity, associated with diabetes risk
  • Inappropriate secretion, associated with hypoglycemia
  • See also
  • References
  • External links

Hyperinsulinism refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and blood levels are closely related to the level of glucose in the blood, so that a given level of insulin can be normal for one blood glucose level but low or high for another. Hyperinsulinism can be associated with several types of medical problems, which can be roughly divided into two broad and largely non-overlapping categories: those tending toward reduced sensitivity to insulin and high blood glucose levels (hyperglycemia), and those tending toward excessive insulin secretion and low glucose levels (hypoglycemia).

==Signs and symptoms== Hyperinsulinism due to reduced insulin sensitivity is usually asymptomatic. In contrast, hyperinsulinemic hypoglycemia can produce any of the entire range of hypoglycemic symptoms, from shakiness and weakness, to seizures or coma.

Excerpted from Wikipedia’s “hyperinsulinism” article, available under the CC BY-SA 4.0 licence.