EntityQ124407· pop 44· linked from 1,241 articles

type-1 diabetes

Also known as IDDM, insulin-dependent diabetes mellitus, type I diabetes mellitus, T1DM, insulin dependent diabetes, juvenile diabetes, diabetes mellitus juvenile type, DIABETES MELLITUS, INSULIN-DEPENDENT; IDDM

autoimmune disease, a form of diabetes mellitus that occurs when insulin-producing cells are destroyed by the immune system

Key facts

Other names: Type 1 diabetes mellitus, insulin-dependent diabetes, insulin-dependent diabetes mellitus (IDDM), juvenile diabetes, childhood-onset diabetes
Pronunciation: / d aɪ ə ˈ b iː t iː z /
Specialty: Endocrinology
Symptoms: Frequent urination , increased thirst , weight loss
Complications: Diabetic ketoacidosis , severe hypoglycemia , cardiovascular disease , and damage to the eyes, kidneys, and nerves
Usual onset: At any age; over days to weeks
Duration: Lifelong
Causes: Body does not produce enough insulin
Risk factors: Family history, celiac disease , autoimmune diseases
Diagnostic method: High blood sugar levels, autoantibodies targeting insulin-producing cells
Prevention: Teplizumab (Delays onset but does not permanently prevent onset of disease)
Treatment: Monitoring blood sugar, injected insulin , managing diet
Prognosis: 10-12 years shorter life expectancy
Frequency: 9 million cases globally

via Wikipedia infobox

Research

113,582 papers

Type 1 Diabetes Mellitus and Cognitive Impairments: A Systematic Review.Journal of Alzheimer's disease : JAD · 2017
Exercise and Type 1 Diabetes.Advances in experimental medicine and biology · 2020
Mapping of Type 1 Diabetes Mellitus.Current diabetes reviews · 2020
Type 1 Diabetes Mellitus and Vitamin D.International journal of molecular sciences · 2025
Lipid metabolism in type 1 diabetes mellitus: Pathogenetic and therapeutic implications.Frontiers in immunology · 2022

via PubMed

Wikidata facts

Image: Blue circle for diabetes.svg

Show 5 more facts

Commons category: Diabetes mellitus type 1
NCI Thesaurus ID: C2986
ICPC 2 ID: T89
exact match: purl.obolibrary.org/obo/HP_0100651
social media followers: 48845

Sources (6)

via Wikidata · CC0

~40 min read

Article

Type 1 diabetes (T1D), or type 1 diabetes mellitus, is an autoimmune disease that occurs when the body's immune system destroys beta cells in the pancreas that produce the hormone insulin. Insulin is required by the body to store and convert blood sugar into energy. T1D results in high blood sugar levels in the body prior to treatment. Common symptoms include frequent urination, increased thirst, increased hunger, weight loss, and other complications. Additional symptoms may include blurry vision, tiredness, and slow wound healing (owing to impaired blood flow). While some cases take longer, symptoms usually appear within weeks or a few months.

The cause of type 1 diabetes is not completely understood, but it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves an autoimmune destruction of the insulin-producing beta cells in the pancreas. Diabetes is diagnosed by testing the level of sugar or glycated hemoglobin (HbA1C) in the blood.