Structure via PubChem · Public domain (PubChem)
icaridin
Sign in to saveAlso known as picaridin, propidine
Picaridin, also known as icaridin, is an insect repellent which can be used directly on skin or clothing. It has broad efficacy against various arthropods such as mosquitos, ticks, gnats, flies and fleas, and is almost colorless and odorless. A study performed in 2010 showed that picaridin spray and cream at the 20% concentration provided 12 hours of protection against ticks. Unlike DEET, picaridin does not dissolve plastics, synthetics or sealants, is odorless and non-greasy and presents a lower risk of toxicity when used with sunscreen, as it may reduce skin absorption of both compounds.
Chemical data
- Formula
- C12H23NO3
- Molecular weight
- 229.32 g/mol
- IUPAC name
- butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate
- SMILES
- CCC(C)OC(=O)N1CCCCC1CCO
- InChIKey
- QLHULAHOXSSASE-UHFFFAOYSA-N
- XLogP
- 2
- Polar surface area
- 49.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 229.168
Show 4 more facts
- Commons category
- Icaridin
- chemical formula
- C₁₂H₂₃NO₃
- canonical SMILES
- CCC(C)OC(=O)N1CCCCC1CCO
- different from
- icariin
Sources (6)
via Wikidata · CC0
~7 min read
Encyclopedic overview
9 sectionsContents
- Effectiveness
- Adverse effects
- Environmental impact
- Mechanism of action
- Chemistry
- Commercial products
- See also
- References
- External links
Picaridin, also known as icaridin, is an insect repellent which can be used directly on skin or clothing. It has broad efficacy against various arthropods such as mosquitos, ticks, gnats, flies and fleas, and is almost colorless and odorless. A study performed in 2010 showed that picaridin spray and cream at the 20% concentration provided 12 hours of protection against ticks. Unlike DEET, picaridin does not dissolve plastics, synthetics or sealants, is odorless and non-greasy and presents a lower risk of toxicity when used with sunscreen, as it may reduce skin absorption of both compounds.
The name picaridin was proposed as an International Nonproprietary Name (INN) to the World Health Organization (WHO), but the official name that has been approved by the WHO is icaridin. The chemical is part of the piperidine family, along with many pharmaceuticals and alkaloids such as piperine, which gives black pepper its spicy taste.
Excerpted from Wikipedia’s “icaridin” article, available under the CC BY-SA 4.0 licence.