iloprost
Sign in to saveAlso known as ZK-00036374, (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]hexahydro-2(1H)-pentalenylidene]pentanoic acid, (RS)-iloprost
Iloprost, sold under the brand name Ventavis among others, is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon, frostbite, and other conditions in which the blood vessels are constricted and blood cannot flow to the tissues. Iloprost is a prostacyclin mimetic.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443868674
- Drug.image
- Iloprost 2D structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- Iloprost.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Ventavis, Ilomedine, Aurlumyn
- Drug.MedlinePlus
- a612032
- Drug.DailyMedID
- Iloprost
- Drug.routes_of_administration
- Inhalation, intravenous
- Drug.ATC_prefix
- B01
- Drug.ATC_suffix
- AC11
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.bioavailability
- Not determined
via Wikipedia infobox
~5 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Pharmacology
- Contraindications
- Side effects
- References
- Further reading
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443868674 | image = Iloprost 2D structure.svg | image_class = skin-invert-image | width = 250 | alt = | image2 = Iloprost.png | image_class2 = bg-transparent | pronounce = | tradename = Ventavis, Ilomedine, Aurlumyn | Drugs.com = | MedlinePlus = a612032 | DailyMedID = Iloprost | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = Inhalation, intravenous | class = | ATC_prefix = B01 | ATC_suffix = AC11 | ATC_supplemental = | legal_US = Rx-only | legal_US_comment = | legal_EU = Rx-only | legal_EU_comment = | legal_status = Rx-only
| bioavailability = Not determined | metabolism = Via β-oxidation to inactive tetranor-iloprost | elimination_half-life = 20–30 minutes | excretion = Kidney (68%) and fecal (12%) | protein_bound = 60%
Excerpted from Wikipedia’s “iloprost” article, available under the CC BY-SA 4.0 licence.
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