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indoprofen
EntityQ3798358· pop 10· linked from 282 articles

indoprofen

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Also known as K-4277, 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone, K 4277, alpha-(4-(1-Oxo-2-isoindolinyl)phenyl)propionic acid, 1-Oxo-2-(p-((alpha-methyl)carboxymethyl)phenyl)isoindoline

Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.

Wikidata facts

Mass
281.105
Has use
medication
Show 4 more facts
chemical formula
C₁₇H₁₅NO₃
canonical SMILES
CC(C1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O)C(=O)O
World Health Organisation international non-proprietary name
indoprofen
Commons category
Indoprofen
Sources (2)

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Encyclopedic overview

3 sections
Contents
  • Synthesis
  • See also
  • References

Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.

Excerpted from Wikipedia’s “indoprofen” article, available under the CC BY-SA 4.0 licence.

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