Structure via PubChem · Public domain (PubChem)
firocoxib
Sign in to saveAlso known as 3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5,5-dimethylfuranone, Equioxx
Firocoxib, sold under the brand names Equioxx and Previcox among others, is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, approved for use in horses (Equioxx) and for use in dogs (Previcox). Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use in human medicine.
Chemical data
- Formula
- C17H20O5S
- Molecular weight
- 336.4 g/mol
- IUPAC name
- 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
- SMILES
- CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C
- InChIKey
- FULAPETWGIGNMT-UHFFFAOYSA-N
- XLogP
- 2.2
- Polar surface area
- 78.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 336.103
Show 5 more facts
- canonical SMILES
- CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C
- Commons category
- Firocoxib
- subject has role
- COX-2 inhibitor
- chemical formula
- C₁₇H₂₀O₅S
- World Health Organisation international non-proprietary name
- firocoxib
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Firocoxib, sold under the brand names Equioxx and Previcox among others, is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, approved for use in horses (Equioxx) and for use in dogs (Previcox). Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use in human medicine.
Firocoxib, manufactured by Merial, was approved for veterinary use in the United States for dogs in July 2004, and for horses in July 2007, as an oral paste (Equioxx) and July 2016, as tablets.
Excerpted from Wikipedia’s “firocoxib” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0