dazoxiben
Sign in to saveAlso known as Benzoic acid, 4-(2-(1H-imidazol-1-yl)ethoxy)-, Dazoxibenum, Dazoxibene
Dazoxiben is an orally active thromboxane synthase inhibitor. It has shown a significant clinical improvement in patients with Raynaud's syndrome.
Research
376 papers- Dazoxiben.Lancet (London, England) · 1983
- Raynaud disease.The Journal of hand surgery · 2014
- Dazoxiben in human sepsis and adult respiratory distress syndrome.Clinical pharmacology and therapeutics · 1985
- Dazoxiben in stable angina.Lancet (London, England) · 1983
- Selective inhibition of thromboxane synthesis with dazoxiben in animals and man.Thrombosis research. Supplement · 1983
via PubMed
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Dazoxiben is an orally active thromboxane synthase inhibitor. It has shown a significant clinical improvement in patients with Raynaud's syndrome.
==Synthesis== thumb|center|500px|Dazoxiben synthesis: One convenient synthesis starts with the O-chloroethyl ether of p-hydroxybenzamide and proceeds bydisplacement with imidazole to give 2. Hydrolysis of the amide function completes the synthesis of dazoxiben.
Excerpted from Wikipedia’s “dazoxiben” article, available under the CC BY-SA 4.0 licence.