ING1

Name

inhibitor of growth family member 1

Type

protein-coding

Position

110,712,736–110,748,944 (+)

Aliases

p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

Ensembl

ENSG00000153487

RefSeq RNA

NM_001267728.1, NM_005537.5, NM_198217.3, NM_198218.3, NM_198219.3

RefSeq protein

NP_001254657.1, NP_005528.4, NP_937860.1, NP_937861.1, NP_937862.1

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

inhibitor of growth family member 1

Symbol

ING1

Biotype

Protein coding

Organism

Homo sapiens

Location

13:110,712,736-110,748,944

Strand

Forward (+)

Assembly

GRCh38

• ING1 and ING2: multifaceted tumor suppressor genes.Cellular and molecular life sciences : CMLS · 2013
• The tumor suppressor ING1: structure and function.Experimental cell research · 2001
• ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat.European journal of cell biology · 2023
• CG7379 and ING1 suppress cancer cell invasion by maintaining cell-cell junction integrity.Open biology · 2021
• Different HATS of the ING1 gene family.Trends in cell biology · 2002

via PubMed

Wikidata facts

Instance of

gene

Image

ING1 .png

via Wikidata · CC0