IRX5
Sign in to saveAlso known as HMMS, IRX-2a, IRXB2, iroquois homeobox 5
Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene.
Gene data
IRX5- Name
- iroquois homeobox 5
- Type
- protein-coding
- Position
- 54,930,779–54,934,485 (+)
- Aliases
- HMMS, IRX-2a, IRXB2
- Ensembl
- ENSG00000176842
- RefSeq RNA
- NM_001252197.1, NM_005853.6, XM_011522809.1, XM_054379377.1
- RefSeq protein
- NP_001239126.1, NP_005844.4, XP_011521111.1, XP_054235352.1
This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
iroquois homeobox 5
- Symbol
- IRX5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:54,930,779-54,934,485
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene.
== Function ==
Excerpted from Wikipedia’s “IRX5” article, available under the CC BY-SA 4.0 licence.