JUNB
Sign in to saveAlso known as AP-1, JunB proto-oncogene, AP-1 transcription factor subunit
gen van de soort Homo sapiens
Gene data
JUNB- Name
- JunB proto-oncogene, AP-1 transcription factor subunit
- Type
- protein-coding
- Position
- 12,791,486–12,793,315 (+)
- Aliases
- AP-1
- Ensembl
- ENSG00000171223
- RefSeq RNA
- NM_002229.3
- RefSeq protein
- NP_002220.1
Enables sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor AP-1 complex. Biomarker of Hodgkin's lymphoma and anaplastic large cell lymphoma. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
regulation of DNA-templated transcriptionregulation of transcription by RNA polymerase IIregulation of transcription by RNA polymerase IIgene expressionregulation of cell population proliferationpositive regulation of transcription by RNA polymerase IIpositive regulation of transcription by RNA polymerase IIpositive regulation of transcription by RNA polymerase II
Molecular function
RNA polymerase II transcription regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA bindingDNA binding
Pathways
via MyGene.info
Gene · Ensembl
JunB proto-oncogene, AP-1 transcription factor subunit
- Symbol
- JUNB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:12,791,486-12,793,315
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7390
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3726
- genomic end
- 12904124
- genomic start
- 12791486
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.13
- expressed in
- trachea
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