KLF5

Name

KLF transcription factor 5

Type

protein-coding

Position

73,054,976–73,077,586 (+)

Aliases

BTEB2, CKLF, IKLF

Ensembl

ENSG00000102554

RefSeq RNA

NM_001286818.2, NM_001730.5, XM_047430553.1, XM_054374881.1

RefSeq protein

NP_001273747.1, NP_001721.2, XP_047286509.1, XP_054230856.1

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013].

via MyGene.info

Gene · Ensembl

KLF transcription factor 5

Symbol

KLF5

Biotype

Protein coding

Organism

Homo sapiens

Location

13:73,054,976-73,077,586

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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