L-arginine
thumb|Arginine ball and stick model spinning Arginine is the amino acid with the formula (H2N)(HN)CN(H)(CH2)3CH(NH2)CO2H. The molecule features a guanidino group appended to a standard amino acid framework. At physiological pH, the carboxylic acid is deprotonated (−CO2−) and both the amino and guanidino groups are protonated, resulting in a cation. Only the L-arginine (symbol Arg or R) enantiomer is found naturally. Arg residues are common components of proteins. It is encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG. The guanidine group in arginine is the precursor for the biosynthesis
AI overview
L-arginine is a naturally occurring amino acid—a building block of proteins—that features a distinctive guanidino group in its molecular structure and carries a positive charge in the body. It is important because it is commonly found in proteins and serves as a precursor for the biosynthesis of other biological molecules.
AI-generated from the Wikipedia summary — may contain errors.
Research
151,142 papers- L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.Cell · 2016
- L-Arginine in diabetes: clinical and preclinical evidence.Cardiovascular diabetology · 2023
- L-arginine metabolism as pivotal interface of mutual host-microbe interactions in the gut.Gut microbes · 2023
- l-Arginine: A multifaceted regulator of diabetic cardiomyopathy.Biochemical and biophysical research communications · 2025
- l-arginine production in Corynebacterium glutamicum: manipulation and optimization of the metabolic process.Critical reviews in biotechnology · 2021
via PubMed
Article
20 sectionsContents
- History
- Sources
- Production
- Dietary sources
- Biosynthesis
- Function
- Proteins
- Precursor
- Structure
- Research
- Growth hormone
- Herpes simplex virus (cold sores)
- High blood pressure
- Schizophrenia
- Raynaud's phenomenon
- Safety and potential drug interactions
- See also
- References
- Sources
- External links
thumb|Arginine ball and stick model spinning Arginine is the amino acid with the formula (H2N)(HN)CN(H)(CH2)3CH(NH2)CO2H. The molecule features a guanidino group appended to a standard amino acid framework. At physiological pH, the carboxylic acid is deprotonated (−CO2−) and both the amino and guanidino groups are protonated, resulting in a cation. Only the L-arginine (symbol Arg or R) enantiomer is found naturally. Arg residues are common components of proteins. It is encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG. The guanidine group in arginine is the precursor for the biosynthesis of nitric oxide. Like all amino acids, it is a white, water-soluble solid.
The one-letter symbol R was assigned to arginine for its phonetic similarity in English.
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