Also known as CGB4, LSH-B, hLHB, HH23, Luteinizing hormone beta polypeptide, LSH-beta, Luteinizing hormone subunit beta
protein-coding gene in the species Homo sapiens
Gene data
LHB- Name
- luteinizing hormone subunit beta
- Type
- protein-coding
- Position
- 49,015,980–49,017,091 (−)
- Aliases
- CGB4, HH23, LSH-B, LSH-beta
- Ensembl
- ENSG00000104826
- RefSeq RNA
- NM_000894.3, XM_047438832.1, XM_054321018.1
- RefSeq protein
- NP_000885.1, XP_047294788.1, XP_054176993.1
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
Show 6 more facts
- HomoloGene ID
- 81806
- exact match
- identifiers.org/ncbigene/3972
- genomic end
- 49017091
- genomic start
- 49519237
- cytogenetic location
- 19q13.33
- Commons category
- Luteinising hormone
Sources (3)
via Wikidata · CC0
Available in 11 languages
via Wikidata sitelinks · CC0