GGH

Also known as GH, gamma-glutamyl hydrolase, GATD10

protein-coding gene in the species Homo sapiens

Gene data

GGH

Name: gamma-glutamyl hydrolase
Type: protein-coding
Position: 63,014,881–63,039,407 (−)
Aliases: GATD10, GH
Ensembl: ENSG00000137563
RefSeq RNA: NM_001410926.1, NM_003878.3
RefSeq protein: NP_001397855.1, NP_003869.1

This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

tetrahydrofolylpolyglutamate metabolic process

Molecular function

protein binding exopeptidase activity omega peptidase activity omega peptidase activity hydrolase activity gamma-glutamyl-peptidase activity gamma-glutamyl-peptidase activity gamma-glutamyl-peptidase activity

Cellular component

extracellular region extracellular region extracellular region nucleus lysosome lysosome vacuole endoplasmic reticulum

Pathways

Folate biosynthesis - Homo sapiens (human)Innate Immune System Immune System Neutrophil degranulation Fluoropyrimidine Activity

via MyGene.info

Gene · Ensembl

gamma-glutamyl hydrolase

Symbol: GGH
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:63,014,881-63,039,407
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein GGH PDB 1l9x.png

Show 8 more facts

HomoloGene ID: 2881
genomic start: 63014881
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/8836
genomic end: 63039407
chromosome: human chromosome 8
cytogenetic location: 8q12.3
expressed in: glomerulus

Sources (4)

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via Wikidata sitelinks · CC0

GGH