(+)-matrine
Sign in to saveAlso known as matrine, (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
Matrine is an alkaloid found in plants from the family Fabaceae. It has a variety of pharmacological effects, including in-vitro anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism.
Wikidata facts
- Mass
- 248.188863388
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- Commons category
- Matrine
- found in taxon
- Sophora davidii
- chemical formula
- C₁₅H₂₄N₂O
- canonical SMILES
- C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1
- isomeric SMILES
- O=C1CCC[C@@H]2[C@H]3CCCN4CCC[C@@H](CN12)[C@@H]34
- has characteristic
- bitterness
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Encyclopedic overview
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Matrine is an alkaloid found in plants from the family Fabaceae. It has a variety of pharmacological effects, including in-vitro anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism.
Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Matrine can be commercially extracted from the traditional Chinese medical herb Sophora flavescens Ait.
Excerpted from Wikipedia’s “(+)-matrine” article, available under the CC BY-SA 4.0 licence.