L1 cell adhesion molecule
Sign in to saveAlso known as L1CAM, neural cell adhesion molecule L1, antigen identified by monoclonal antibody R1, Neural cell adhesion molecule L1
mammalian protein found in Homo sapiens
In the Vinony graph
Vinony's link graph records 418 inbound references to L1 cell adhesion molecule, and connects out to amino acid, PubMed and base pair.
Vinony files it under Cell adhesion proteins, Clusters of differentiation and Genes on human chromosome X.
Vinony links it to 5 Wikipedia language editions.
Protein · UniProt
Neural cell adhesion molecule L1
- Gene
- L1CAM
- Organism
- Homo sapiens (Human)
- Length
- 1,257 aa
- Molecular mass
- 140,003 Da
- Evidence
- 1: Evidence at protein level
Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity
Swiss-Prot (reviewed) · via UniProt
Research
2,705 papers- L1 cell adhesion molecule as a therapeutic target in cancer.Expert review of anticancer therapy · 2016
- Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron-derived EVs.Journal of extracellular vesicles · 2024
- L1 Cell Adhesion Molecule in Cancer, a Systematic Review on Domain-Specific Functions.International journal of molecular sciences · 2019
- Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro.Biomolecules · 2022
- L1 cell adhesion molecule (L1CAM) in invasive tumors.Cancer letters · 2009
via PubMed
Wikidata facts
- Instance of
- protein
Show 2 more facts
- found in taxon
- Homo sapiens
- Commons category
- L1 (protein)
via Wikidata · CC0