میراگینین

Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. It has also been researched for its use to potentially manage symptoms of opioid withdrawal. It is a partial agonist of the mu-opioid receptors; and as such can produce effects similar to those of classical opioids such as morphine.

Key facts

Drug.bioavailability: 21%
Drug.drug_name: Mitragynine
Drug.image: Mitragynine v2.svg
Drug.image_class: skin-invert-image
Drug.image2: Mitragynine molecule ball.png
Drug.image_class2: bg-transparent
Drug.legal_AU: S8
Drug.legal_BR: B1
Drug.legal_CA: Unscheduled
Drug.legal_DE: NPSG
Drug.legal_NZ: Unscheduled
Drug.legal_UK: PSA
Drug.legal_US: unscheduled
Drug.legal_UN: unscheduled
Drug.legal_status: In general legal for medical and research uses as a research chemical.
Drug.routes_of_administration: By mouth
Drug.IUPAC_name: methyl (16E)-9,17-dimethoxy-16,17-didehydro-20β-corynan-16-carboxylate
Drug.metabolites: 7-Hydroxymitragynine

via Wikipedia infobox

Chemical data

Formula: C23H30N2O4
Molecular weight: 398.5 g/mol
IUPAC name: methyl (E)-2-[(2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
SMILES: CC[C@@H]1CN2CCC3=C([C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)NC4=C3C(=CC=C4)OC
InChIKey: LELBFTMXCIIKKX-QVRQZEMUSA-N
XLogP: 3.4
Polar surface area: 63.8 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Has part: oxygen
Mass: 398.221

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chemical formula: C₂₃H₃₀N₂O₄
canonical SMILES: CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC
isomeric SMILES: CC[C@@H]1CN2CCC3=C([C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)NC4=C3C(=CC=C4)OC
Commons category: Mitragynine
found in taxon: Mitragyna speciosa

Sources (2)

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Gallery (3)

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