MMP10
Sign in to saveAlso known as SL-2, STMY2, matrix metallopeptidase 10
Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.
Gene data
MMP10- Name
- matrix metallopeptidase 10
- Type
- protein-coding
- Position
- 102,770,502–102,780,628 (−)
- Aliases
- SL-2, STMY2
- Ensembl
- ENSG00000166670
- RefSeq RNA
- NM_002425.3
- RefSeq protein
- NP_002416.1
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein MMP10 PDB 1q3a.png
Show 5 more facts
- HomoloGene ID
- 20546
- genomic start
- 102770502
- exact match
- identifiers.org/ncbigene/4319
- genomic end
- 102651359
- cytogenetic location
- 11q22.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.
== Function ==