monobactam antibiotic
Also known as monobactam, monobactams
class=skin-invert-image|thumb|285px|Tigemonam Monobactams are bacterially-produced monocyclic β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams.
Key facts
- Drug class.Name
- Aztreonam
- Drug class.Image
- Aztreonam structure.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Caption
- Aztreonam. (The four-membered ring at the bottom is the β-lactam. There is a second thiazole ring, but it is not fused to the β-lactam ring.)
- Drug class.Use
- Bacterial infection
- Drug class.ATC_prefix
- J01DF
- Drug class.MeshID
- D008997
via Wikipedia infobox
Research
2,700 papersvia PubMed
Article
5 sectionsContents
- Pharmacology
- Adverse effects
- Research
- References
- External links
class=skin-invert-image|thumb|285px|Tigemonam Monobactams are bacterially-produced monocyclic β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams.
Monobactams are narrow-spectrum antibiotics effective only against (strictly or facultatively) aerobic Gram-negative bacilli, exhibiting a high level of resistance to beta-lactamases of these organisms. Due to their narrow spectrum, monobactams can be used to treat infections by susceptible bacteria without disrupting the patient's microbiota. Monobactams are nevertheless seldom used.