monobactam antibiotic
Sign in to saveAlso known as monobactam, monobactams
class=skin-invert-image|thumb|285px|Tigemonam Monobactams are bacterially-produced monocyclic β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams.
Key facts
- Drug class.Name
- Aztreonam
- Drug class.Image
- Aztreonam structure.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Caption
- Aztreonam. (The four-membered ring at the bottom is the β-lactam. There is a second thiazole ring, but it is not fused to the β-lactam ring.)
- Drug class.Use
- Bacterial infection
- Drug class.ATC_prefix
- J01DF
- Drug class.MeshID
- D008997
via Wikipedia infobox
Research
2,700 papersvia PubMed
Wikidata facts
- Subclass of
- β-lactam antibiotic
Show 2 more facts
- topic's main category
- Category:Monobactam antibiotics
- Commons category
- Monobactams
Sources (1)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Pharmacology
- Adverse effects
- Research
- References
- External links
class=skin-invert-image|thumb|285px|Tigemonam Monobactams are bacterially-produced monocyclic β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams.
Monobactams are narrow-spectrum antibiotics effective only against (strictly or facultatively) aerobic Gram-negative bacilli, exhibiting a high level of resistance to beta-lactamases of these organisms. Due to their narrow spectrum, monobactams can be used to treat infections by susceptible bacteria without disrupting the patient's microbiota. Monobactams are nevertheless seldom used.
Excerpted from Wikipedia’s “monobactam antibiotic” article, available under the CC BY-SA 4.0 licence.