MRPL15

Also known as L15mt, MRP-L15, MRP-L7, RPML7, HSPC145, mitochondrial ribosomal protein L15

protein-coding gene in the species Homo sapiens

Gene data

MRPL15

Name: mitochondrial ribosomal protein L15
Type: protein-coding
Aliases: HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, uL15m

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008].

via MyGene.info