MRPL15
Sign in to saveAlso known as L15mt, MRP-L15, MRP-L7, RPML7, HSPC145, mitochondrial ribosomal protein L15
protein-coding gene in the species Homo sapiens
Gene data
MRPL15- Name
- mitochondrial ribosomal protein L15
- Type
- protein-coding
- Position
- 54,135,183–54,149,588 (+)
- Aliases
- HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, uL15m
- Ensembl
- ENSG00000137547
- RefSeq RNA
- NM_014175.4
- RefSeq protein
- NP_054894.1
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mitochondrial ribosomal protein L15
- Symbol
- MRPL15
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:54,135,183-54,149,588
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 32210
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29088
- genomic end
- 54148514
- genomic start
- 54135241
- chromosome
- human chromosome 8
- cytogenetic location
- 8q11.23
- expressed in
- gonad
Sources (4)
via Wikidata · CC0