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GeneQ18039586· pop 5· linked from 207 articles

Also known as L15mt, MRP-L15, MRP-L7, RPML7, HSPC145, mitochondrial ribosomal protein L15

protein-coding gene in the species Homo sapiens

Gene data

MRPL15
Name
mitochondrial ribosomal protein L15
Type
protein-coding
Position
54,135,183–54,149,588 (+)
Aliases
HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, uL15m
RefSeq RNA
NM_014175.4
RefSeq protein
NP_054894.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein L15

Symbol
MRPL15
Biotype
Protein coding
Organism
Homo sapiens
Location
8:54,135,183-54,149,588
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
32210
found in taxon
Homo sapiens
genomic end
54148514
genomic start
54135241
cytogenetic location
8q11.23
expressed in
gonad
Sources (4)

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