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EntityQ6995920· pop 15· linked from 494 articles

Also known as HKI 272, HKI-272

Neratinib (INN), sold under the brand name Nerlynx, is a tyrosine kinase inhibitor anti-cancer medication used for the treatment of breast cancer.

~5 min read

Encyclopedic overview

11 sections
Contents
  • Medical uses
  • Contraindications
  • Adverse effects
  • Interactions
  • Pharmacology
  • Cell biology
  • Chemistry
  • History
  • Brand names
  • References
  • External links

Neratinib (INN), sold under the brand name Nerlynx, is a tyrosine kinase inhibitor anti-cancer medication used for the treatment of breast cancer.

The most common side effect is diarrhea, which affects nearly all patients. Other common side effects include nausea (feeling sick), vomiting, tiredness, belly pain, rash, decreased appetite, stomatitis (sore, inflamed mouth), and muscle spasms.

Excerpted from Wikipedia’s “neratinib” article, available under the CC BY-SA 4.0 licence.