NFATC3
Sign in to saveAlso known as NFAT4, NFATX, nuclear factor of activated T-cells 3, nuclear factor of activated T cells 3, NF-AT4c
Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.
Gene data
NFATC3- Name
- nuclear factor of activated T cells 3
- Type
- protein-coding
- Position
- 68,084,751–68,229,259 (+)
- Aliases
- NF-AT4c, NFAT4, NFATX, n339260
- Ensembl
- ENSG00000072736
- RefSeq RNA
- NM_004555.4, NM_173163.3, NM_173164.1, NM_173165.3
- RefSeq protein
- NP_004546.1, NP_775186.1, NP_775188.1
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nuclear factor of activated T cells 3
- Symbol
- NFATC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:68,084,751-68,229,259
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 27827
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4775
- genomic end
- 68263162
- genomic start
- 68118654
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.
== Function ==
Excerpted from Wikipedia’s “NFATC3” article, available under the CC BY-SA 4.0 licence.