NFIX
Sign in to saveAlso known as MRSHSS, NF1A, SOTOS2, nuclear factor I X, NF1-X, NF-I/X, CTF, MALNS
Gen der Spezies Homo sapiens
Gene data
NFIX- Name
- nuclear factor I X
- Type
- protein-coding
- Position
- 12,995,401–13,098,796 (+)
- Aliases
- CTF, MALNS, MRSHSS, NF-I/X, NF1-X, NF1A, SOTOS2
- Ensembl
- ENSG00000008441
- RefSeq RNA
- NM_001271043.2, NM_001271044.3, NM_001365902.3, NM_001365982.2, NM_001365983.2
- RefSeq protein
- NP_001257972.1, NP_001257973.1, NP_001352831.1, NP_001352911.1, NP_001352912.1
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012].
Gene Ontology
Biological process
Molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activityDNA-binding transcription factor activityprotein bindingsequence-specific double-stranded DNA binding
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
nuclear factor I X
- Symbol
- NFIX
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:12,995,401-13,098,796
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 1872
- genomic end
- 13098796
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4784
- genomic start
- 12995475
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.13
- genetic association
- Marshall–Smith syndrome
- expressed in
- urethra
via Wikidata · CC0