NMBR
Sign in to saveAlso known as BB1, NMB-R, neuromedin B receptor, BB1R, BRS1
gen van de soort Homo sapiens
Gene data
NMBR- Name
- neuromedin B receptor
- Type
- protein-coding
- Position
- 142,058,330–142,147,122 (−)
- Aliases
- BB1, BB1R, BRS1, NMB-R
- Ensembl
- ENSG00000135577
- RefSeq RNA
- NM_001324307.2, NM_001324308.2, NM_002511.4
- RefSeq protein
- NP_001311236.1, NP_001311237.1, NP_002502.2
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
neuromedin B receptor
- Symbol
- NMBR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:142,058,330-142,147,122
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI