NPSR1

Also known as ASRT2, GPR154, GPRA, NPSR, PGR14, VRR1, neuropeptide S receptor 1

protein-coding gene in the species Homo sapiens

Gene data

NPSR1

Name: neuropeptide S receptor 1
Type: protein-coding
Position: 34,658,218–34,878,332 (+)
Aliases: ASRT2, FNSS3, GPR154, GPRA, NPSR, PGR14, VRR1
Ensembl: ENSG00000187258
RefSeq RNA: NM_001300933.2, NM_001300934.2, NM_001300935.2, NM_207172.2, NM_207173.2
RefSeq protein: NP_001287862.1, NP_001287863.1, NP_001287864.1, NP_997055.1, NP_997056.1

This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].