N-甲基-D-天門冬胺酸受體
Sign in to saveAlso known as N-Methyl-D-Aspartate receptor, N-Methylaspartate receptor, NMDA-selective glutamate receptor, NMDAR, Receptors, N-Methyl-D-Aspartate, N-methyl-D-aspartate receptors
glutamate receptor and ion channel protein found in nerve cells
Research
52,365 papers- Mechanisms of NMDA receptor regulation.Current opinion in neurobiology · 2023
- Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells.Cell · 2023
- Neurocritical care for Anti-NMDA receptor encephalitis.Biomedical journal · 2020
- The NMDA receptor antagonists memantine and ketamine as anti-migraine agents.Naunyn-Schmiedeberg's archives of pharmacology · 2023
- [Neuropsychiatric aspects of anti-NMDA receptor encephalitis].Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2021
via PubMed
Wikidata facts
- Subclass of
- ionotropic glutamate receptor, metazoa
- Image
- NMDA receptor.jpg
Show 2 more facts
- facilitates flow of
- calcium
- Commons category
- N-methyl-D-aspartate receptors
Sources (2)
via Wikidata · CC0
Article · 中文
N-甲基-D-天門冬胺酸受體（英語：N-methyl-D-aspartate receptor，簡稱NMDA受體或NMDAR）為受體，是一個主要的分子裝置，控制突觸的可塑性與記憶功能。 NMDA受體是一種離子型麩胺酸鹽受體的特別型態。（N-甲基-D-天門冬胺酸）是一種選擇性致效劑，可以與NMDA受體結合，但是無法和其他麩胺酸鹽受體結合。NMDA受體的結合，會導致離子通道非選擇性地開啟，使陽離子通過，進而使改變至接近0毫伏特。NMDA受體進行活化，必須依賴電壓，這會導致離子通道會阻擋細胞外的Mg2+與Zn2+離子通過，並允許Na+離子與少量Ca2+離子流入細胞，以及使K+離子流出細胞，並保持電壓的依賴性。
Abstract from DBpedia / Wikipedia · CC BY-SA