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2-fluorodeschloroketamine

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Also known as 2-Fl-2'-Oxo-PCM, 2-FDCK, fluoroketamine

2-Fluorodeschloroketamine (also known as '''2'-Fl-2-Oxo-PCM, fluoroketamine, and 2-FDCK''') is a dissociative anesthetic related to ketamine. Its sale and use as a designer drug has been reported in various countries. It is an analogue of ketamine where the chlorine group has been replaced by fluorine. Due to its recent emergence, the pharmacological specifics of the compound are mostly unclear, but effects are reported to be similar to its parent compound, ketamine.

Wikidata facts

Mass
221.121592352
Show 2 more facts
canonical SMILES
CNC1(c2ccccc2F)CCCCC1=O
chemical formula
C₁₃H₁₆FNO
Sources (2)

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~6 min read

Encyclopedic overview

15 sections
Contents
  • History
  • Chemistry
  • Structure
  • Synthesis
  • Detection
  • Pharmacology
  • Metabolism
  • Pharmacodynamics
  • Comparison to other halogen-substituted ketamine variants
  • Adverse effects
  • Possible effects and dangers
  • Legal status
  • United States
  • See also
  • References

2-Fluorodeschloroketamine (also known as '''2'-Fl-2-Oxo-PCM, fluoroketamine, and 2-FDCK''') is a dissociative anesthetic related to ketamine. Its sale and use as a designer drug has been reported in various countries. It is an analogue of ketamine where the chlorine group has been replaced by fluorine. Due to its recent emergence, the pharmacological specifics of the compound are mostly unclear, but effects are reported to be similar to its parent compound, ketamine.

== History == The synthesis of 2-FDCK was first described in a 2013 paper as part of a larger effort to synthesize and evaluate new anesthetic drugs based on ketamine and its analogues. Ketamine itself was first introduced in 1964 and was approved for clinical use in 1970. Since then it has become one of the most important and applicable general anesthetics as well as a popular recreational drug.

Excerpted from Wikipedia’s “2-fluorodeschloroketamine” article, available under the CC BY-SA 4.0 licence.

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