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ibogamine

Structure via PubChem · Public domain (PubChem)

EntityQ5984343· pop 7· linked from 843 articles

Ibogamine is an anti-convulsant, anti-addictive, CNS stimulant alkaloid found in Tabernanthe iboga and Crepe Jasmine (Tabernaemontana divaricata). Basic research related to how addiction affects the brain has used this chemical.

Chemical data

Formula
C19H24N2
Molecular weight
280.4 g/mol
IUPAC name
(1R,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene
SMILES
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=CC=CC=C45
InChIKey
LRLCVRYKAFDXKU-YGOSVGOTSA-N
XLogP
3.9
Polar surface area
19 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Wikidata facts

Mass
280.194
Show 5 more facts
chemical formula
C₁₉H₂₄N₂
canonical SMILES
CCC1CC2CC3C1N(C2)CCC4=C3NC5=CC=CC=C45
isomeric SMILES
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=CC=CC=C45
Commons category
Ibogamine
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

5 sections
Contents
  • Pharmacology
  • Chemistry
  • Synthesis
  • See also
  • References

Ibogamine is an anti-convulsant, anti-addictive, CNS stimulant alkaloid found in Tabernanthe iboga and Crepe Jasmine (Tabernaemontana divaricata). Basic research related to how addiction affects the brain has used this chemical.

== Pharmacology == Like ibogaine, it has seems to have similar pharmacology. It has effects on KOR, NMDAR, nAChR and serotonin sites. It also inhibits acetylcholinesterase and butyrylcholinesterase.

Excerpted from Wikipedia’s “ibogamine” article, available under the CC BY-SA 4.0 licence.

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