Also known as L8C, PPL8, L8, PPNPW, neuropeptide W
NPW is a gene that in humans encodes Neuropeptide W protein.
Gene data
NPW- Name
- neuropeptide W
- Type
- protein-coding
- Aliases
- L8, L8C, PPL8, PPNPW
The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
neuropeptide W
- Symbol
- NPW
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:2,009,926-2,020,755
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 17727
- exact match
- identifiers.org/ncbigene/283869
- genomic end
- 2070756
- genomic start
- 2059927
- cytogenetic location
- 16p13.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
NPW is a gene that in humans encodes Neuropeptide W protein.
Neuropeptide W (NPW) is an endogenous peptide ligand for GPR8 (MIM 600731), a G protein-coupled receptor.[supplied by OMIM]