NPTX2
Sign in to saveAlso known as NARP, NP-II, NP2, neuronal pentraxin 2
Neuronal pentraxin-2 is a protein that in humans is encoded by the NPTX2 gene.
Gene data
NPTX2- Name
- neuronal pentraxin 2
- Type
- protein-coding
- Aliases
- NARP, NP-II, NP2
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009].
via MyGene.info
Gene · Ensembl
neuronal pentraxin 2
- Symbol
- NPTX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:98,617,254-98,629,870
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/4885
- HomoloGene ID
- 1892
- genomic start
- 98617285
- genomic end
- 98629869
- cytogenetic location
- 7q22.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Neuronal pentraxin-2 is a protein that in humans is encoded by the NPTX2 gene.
== Function ==