NR2F1
Sign in to saveAlso known as BBOAS, BBSOAS, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44
COUP-TF1 (COUP Transcription Factor 1) also known as NR2F1 (Nuclear Receptor subfamily 2, group F, member 1) is a protein that in humans is encoded by the NR2F1 gene. This protein is a member of nuclear hormone receptor family of steroid hormone receptors.
Gene data
NR2F1- Name
- nuclear receptor subfamily 2 group F member 1
- Type
- protein-coding
- Position
- 93,583,222–93,594,611 (+)
- Aliases
- BBOAS, BBSOAS, COUP-TFI, COUPTF1, EAR-3, EAR3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1
- Ensembl
- ENSG00000175745
- RefSeq RNA
- NM_001410754.1, NM_005654.6
- RefSeq protein
- NP_001397683.1, NP_005645.1
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
nuclear receptor subfamily 2 group F member 1
- Symbol
- NR2F1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:93,583,222-93,594,611
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 21158
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7025
- chromosome
- human chromosome 5
- genomic start
- 93583222
- genomic end
- 93594611
- cytogenetic location
- 5q15
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Interactions
- Clinical
- References
- External links
- Further reading
COUP-TF1 (COUP Transcription Factor 1) also known as NR2F1 (Nuclear Receptor subfamily 2, group F, member 1) is a protein that in humans is encoded by the NR2F1 gene. This protein is a member of nuclear hormone receptor family of steroid hormone receptors.
== Function ==
Excerpted from Wikipedia’s “NR2F1” article, available under the CC BY-SA 4.0 licence.