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ORG 20599
Sign in to saveORG-20599 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive allosteric modulator and, at higher concentrations, agonist. It was developed for use as an anaesthetic agent but was never marketed for this purpose, although it is still used in scientific research.
In the Vinony graph
Vinony's link graph records 751 inbound references to ORG 20599, and connects out to ginkgolide, picrotoxin and tetrahydrodeoxycorticosterone.
Vinony files it under 4-Morpholinyl compounds, 5β-Pregnanes and Anticonvulsants.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C25H40ClNO3
- Molecular weight
- 438 g/mol
- IUPAC name
- 2-chloro-1-[(2S,3S,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
- SMILES
- C[C@]12CCC3C(C1CCC2C(=O)CCl)CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C
- InChIKey
- NZFNABGZEQPYBX-NZVKSUHHSA-N
- XLogP
- 4.9
- Polar surface area
- 49.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 437.27
Show 3 more facts
- canonical SMILES
- CC12CCC3C(C1CCC2C(=O)CCl)CCC4C3(CC(C(C4)O)N5CCOCC5)C
- chemical formula
- C₂₅H₄₀ClNO₃
- isomeric SMILES
- C[C@]12CCC3C(C1CCC2C(=O)CCl)CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Chemistry
- References
ORG-20599 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive allosteric modulator and, at higher concentrations, agonist. It was developed for use as an anaesthetic agent but was never marketed for this purpose, although it is still used in scientific research.
==Chemistry==
Excerpted from Wikipedia’s “ORG 20599” article, available under the CC BY-SA 4.0 licence.