File:Osteosarcoma_-_intermed_mag.jpg · Wikimedia Commons · See Wikimedia Commons
osteosarcoma
Sign in to saveAlso known as Osteogenic sarcoma, Skeletal sarcoma, osteoid sarcoma, OSTEOSARCOMA, MALIGNANT, sarcoma of osteoid
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.
Key facts
- Medical condition (new).caption
- Intermediate-magnification micrograph of an osteosarcoma (center and right of image) adjacent to non-malignant bone (left-bottom of image): The top-right of the image has poorly differentiated tumor. Osteoid with a high density of malignant cells is seen between the non-malignant bone and poorly differentiated tumor (H&E stain).
- Medical condition (new).field
- Oncology
- Medical condition (new).name
- Osteosarcoma
- Medical condition (new).image
- Osteosarcoma - intermed mag.jpg
via Wikipedia infobox
Research
48,490 papers- Telangiectatic osteosarcoma.Archives of pathology & laboratory medicine · 2012
- Targeting WNT5B and WNT10B in osteosarcoma.Oncotarget · 2024
- Periosteal Osteosarcoma: Emerging Clinical Concepts, Evolving Treatment Options: A Narrative Review.Current pain and headache reports · 2025
- DNA cytometry of osteosarcoma.Acta orthopaedica Scandinavica. Supplementum · 1988
- Osteosarcoma in Paget's disease of bone.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2006
via PubMed
Wikidata facts
- Subclass of
- childhood cancer
- Image
- Predilection sites of osteosarcoma2.png
Show 5 more facts
- NCI Thesaurus ID
- C9145
- health specialty
- oncology
- Commons category
- Osteosarcoma
- exact match
- purl.obolibrary.org/obo/HP_0002669
- on focus list of Wikimedia project
- WikiProject Medicine
Sources (7)
via Wikidata · CC0
~17 min read
Encyclopedic overview
18 sectionsContents
- Signs and symptoms
- Causes
- Mechanism
- Diagnosis
- Variants
- Treatment
- Prognosis
- Epidemiology
- Other animals
- Risk factors
- Clinical presentation
- Treatment and prognosis
- Molecular alterations
- Cats
- Dinosaurs
- References
- Further reading
- External links
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.
Osteosarcoma is the most common histological form of primary bone sarcoma. It is most prevalent in teenagers and young adults.
Excerpted from Wikipedia’s “osteosarcoma” article, available under the CC BY-SA 4.0 licence.